The one moment that just comes to mind is the burial of the Going Merry. It was the very first time I cried while watching anime.
I'm not an emotional guy or something even close. But that broke my heart.
Another is the Zoro taking up all the damage from Kuma.
Man what a goosebump moment.
Third one is the Strawhats getting send away from Kuma. Holy moly, I was stunned. I started watching the anime and this was really the last few eps before I was up to date After that I started joining forums and reading the manga.
One Piece is really becoming a big part of my life if I relieve it like this. I was so young when I started..